Table 2 Constants*.

r _sb = 10

volume ratios

k₁ = .11

k₂ = .9

k_-2 = .01

gut to blood, blood to body store (hr^-1)

k₃ = 7

k_-3 = 1

k₉ = .1

k_-9 = .01

iAs, blood to liver, liver to liver store (hr^-1)

k₄ = .1

k_-4 = .1

MMAs, blood to liver (hr^-1)

k₅ = .2

k_-5 = .1

k₁₀ = .1

k_-10 = .1

DMAs, blood to liver, liver to liver store (hr^-1)

k₆ = .253

k₇ = .17

k₈ = .85

iAs, MMAs, DMAs, blood to urine (hr^-1)

K _m = 4.6

V _mαx = .7

methylation, iAs → MMAs (μ M or μ M/hr)

K _m = 3

V _mαx = .7

methylation, MMAs → DMAs (μ M or μ M/hr)